ABSTRACT
In order to standardize the dermoscopic criteria for non-neoplastic dermatoses, experts from the International Dermoscopy Society have established "standardization of dermoscopic terminology and basic dermoscopic parameters to evaluate in general dermatology (non-neoplastic dermatoses) : an expert consensus on behalf of the International Dermoscopy Society" . The consensus defined 5 standardized basic parameters and 31 subitems, including vessels (morphology and distribution) , scales (color and distribution) , follicular findings, "other structures" (color and morphology) and "specific clues" , and summarized their previous nomenclature, corresponding histological findings and the main dermatoses involved. The authors explain and elaborate this consensus in order to provide a reference for defining relevant Chinese dermoscopic terminology and basic parameters in the future, and to better standardize the application of dermoscopy in general dermatology.
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Objective To evaluate the application value of dermoscopy in the diagnosis of genital condyloma acuminatum (CA) in men.Methods A total of 122 warts from 66 male patients with suspected genital CA were firstly diagnosed by experienced dermatologists according to macroscopic morphological characteristics of lesions and clinical history of patients.Afterwards,the warts were examined and diagnosed by dermoscopy,and the two diagnosis results were compared with histopathological findings.Results Of 122 suspected warts,100 were diagnosed as CA by naked-eye examination,112 as CA by dermoscopy and 114 as CA by pathological examination.When histopathological findings served as the gold standard,dermoscopy had a sensitivity of 97.4％ and a specificity of 87.5％,and naked-eye examination had a sensitivity of 87.7％ and a specificity of 100％.Under dermoscopy,most male genital warts were pink (98/114,86.0％) and papillary (98/114,86.0％),and had distinct vascular characteristics (107/114,95.5％),which mainly included pleomorphic vessels (102/114,89.5％) and punctate vessels (98/114,86.0％).Conclusion CA has characteristic structures under dermoscopy,so dermoscopy can be used for the diagnosis of genital CA in men.
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OBJECTIVE To collect the document about drug sensitivity in mycoplasma-infected cases in Beijing area and to instruct drug-selecting in clinic treatment. METHODS Drug sensitivity test on 263 Mycoplasma-positive non-gonococcal urethritis(NGU)(mucopurulent cervicitis,MPC)cases was conducted. RESULTS Tetracyclines and minocycline performed the highest sensitivity(94.68%),followed by josamycin(94.30%) and doxycycline(91.63%).Lomefloxacin had the lowest sensitivity(15.59%). CONCLUSIONS Tetracyclines and macrolides can be employed as the first-choice drugs in NGU(MPC)treatment.
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In the paper,a modified ELISA was first developed for the detection of antibody to Ureaplasma urealyticum(UU) in clinical specimens. Antibody to UU in serum of patient was detected by indirect ELISA. In comparison with metabolism inhibition test(MIT), of 22 UU culture-positive individuals, 21 were positive by ELISA and 22 by the MIT with an overall agreement of 95. 5%. IgG antibodies to UU were found in 93.8% and IgM in 30.8% of 81 UU culture-positive patients,whereas IgG antibodies in 2. 5% and IgM in 3.7% of the UU culture-negative group by ELISA. Meantime,serovartype-specific antibody could not be detected by ELISA with type-specific antigen, the cross-reaction might be due to the presence of homogeneous antigens among UU species.